Edmund Tsui Laboratory
Uveitis and Ocular Inflammatory Diseases
Advancing the diagnosis and treatment of uveitis through cutting-edge imaging technologies and clinical trials
Edmund Tsui, M.D., M.S.
Associate Professor
Department of Ophthalmology
Jules Stein Eye Institute
The Tsui Research Group is committed to advancing the field of uveitis through innovative imaging analysis, improved diagnostic tools, and clinical trials. By leveraging advanced imaging modalities such as optical coherence tomography, we aim to quantify objectively intraocular inflammation and enhance diagnostic accuracy in uveitis. Our work also includes developing standardized methodologies for assessing inflammation, and conducting clinical trials to evaluate novel therapeutics in the treatment of uveitis and ocular inflammatory disease.
Our research focuses on these areas:
- Image Analysis: Develop and validate imaging biomarkers using optical coherence tomography (OCT) and other advanced imaging modalities to quantify intraocular inflammation and monitor disease activity in uveitis. This work aims to improve the objectivity of diagnostic assessments, enhance disease monitoring, and guide treatment decisions by leveraging cutting-edge imaging technologies.
- Advanced Diagnostics: Utilize ocular fluid sampling techniques, such as aqueous and vitreous humor analysis, to improve the diagnosis of uveitis. This includes cytokine profiling, pathogen detection, and biomarker discovery to enable precision diagnostics and uncover underlying etiologies of ocular inflammation.
- Clinical Trials: Design and conduct clinical trials to evaluate novel therapies and refine treatment strategies for uveitis and other ocular inflammatory diseases. Our research encompasses immune-modulating therapies, biologics, small molecules, and targeted immunotherapies aimed at reducing inflammation, preventing vision loss, and improving patient outcomes.
These research areas reflect our group’s mission to advance the understanding, diagnosis, and treatment of uveitis and ocular inflammatory diseases through innovation and collaboration.
Recent Publications
Candida Interface Infections After Descemet Stripping Automated Endothelial Keratoplasty.
Tsui E, Fogel E, Hansen K, Talbot EA, Tammer R, Fogel J, Daly ER, Noble J, Caine L, Zegans ME
2016
Relationship between retinal blood flow and arterial oxygen.
Cheng RW, Yusof F, Tsui E, Jong M, Duffin J, Flanagan JG, Fisher JA, Hudson C
2016
Bacterial corneal ulcer associated with common variable immune deficiency.
Tsui E, Deng J, Siedlecki AN, Zegans ME
2016
To Bridge the Gap, Make a Proper Connexin.
Tsui E, Hutnik C
2016
Blurred Vision. Leukemia relapse.
Deng J, Tsui E, Chapman CB
2015
Ophthalmology on social networking sites: an observational study of Facebook, Twitter, and LinkedIn.
Micieli JA, Tsui E
2015
Implementation of a vision-screening program in rural northeastern United States.
Tsui E, Siedlecki AN, Deng J, Pollard MC, Cha S, Pepin SM, Salcone EM
2015
Question: Can you identify this condition? Acute retinal necrosis.
Ford JR, Tsui E, Lahey T, Zegans ME
2013
Answer: Can you identify this condition?
Ford JR, Tsui E, Lahey T, Zegans ME
2013
Increased rates of long-term complications after MammoSite brachytherapy compared with whole breast radiation therapy.
Rosenkranz KM, Tsui E, McCabe EB, Gui J, Underhill K, Barth RJ
2013