Yi-Rong Peng Laboratory

Cells are the building blocks of complex biological systems, exhibiting remarkable diversity in the visual system. Understanding how cell types form, connect, and degenerate is fundamental to uncover the mechanisms behind blinding diseases. The Peng lab leverages multi-omics approaches–genomics, transcriptomics, and proteomics–to decode genetic programs that define cell-type features, unravel the molecular basis of specialized human vision, and identify key signatures driving degeneration in ocular diseases.

The ultimate goal of our research is to provide a fundamental understanding of circuit formation and degeneration in the visual system and to develop therapeutic strategies to prevent or treat vision loss.