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Greg D. Field Laboratory

Visual Processing and Retinal Circuits

Understanding neural computation in the retina

Dr. Gregory Field

Greg D. Field, Ph.D.

Associate Professor

Joan and Jerome Snyder Vision Science Chair

Department of Ophthalmology

Assistant Director of Research

Director, Live Imaging and Functional Evaluation Core

Jules Stein Eye Institute

The Field laboratory investigates how neural circuits in the retina process visual information and adapt to different environmental conditions. Our research combines electrophysiology, imaging, and computational approaches to understand the fundamental principles of retinal computation.

Research Focus Areas:

  • Neural circuits for motion processing
  • Adaptation to different light levels
  • Parallel processing in retinal pathways
  • Computational models of retinal function
  • Visual signal processing and encoding

Our research aims to understand how the retina performs complex computations and adapts to changing environmental conditions. This work provides insights into both fundamental principles of neural computation and potential therapeutic strategies for vision restoration.

Selected Publications

GABAergic inhibition controls receptive field size, sensitivity and response polarity of direction selective ganglion cells near the threshold of vision

Roy S, Yao X, Rathinavelu J, Field GD

Journal of Neuroscience (2024)

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Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa

Scalabrino ML, Thapa M, Wang T, Sampath AP, Chen J, Field GD

Nature Communications (2023)

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Large scale interrogation of retinal cell function by 1-photon light sheet microscopy

Roy S, Wang D, Rudzite AM, Perry B, Scalabrino ML, Gong YY, Sher A, Field GD

Cell Reports Methods (2023)

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Inter-mosaic coordination of retinal receptive fields

Roy S, Jun NY, Davis EL, Pearson J, Field GD

Nature (2021)

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Ignoring correlated activity causes a failure of retinal population codes

Ruda K, Zylberberg J, Field GD

Nature Communications (2020)

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