
Integrating AI, imaging, and genomics for curing retinal disease

Assistant Professor
Department of Ophthalmology
Jules Stein Eye Institute
Dr. Adrian Au applies machine learning algorithms to ocular imaging modalities, including fundus photography and optical coherence tomography (OCT), to extract and quantify retinal biomarkers associated with disease phenotypes. His research emphasizes the integration of these imaging-derived features with genomic datasets to elucidate the molecular and genetic underpinnings of retinal pathology.
Through the fusion of deep learning-based image analysis and genomic frameworks, Dr. Au seeks to advance our understanding of the biological mechanisms driving disease onset, progression, and therapeutic response. His work operates at the intersection of ophthalmology, computational biology, and precision medicine, with the aim of developing clinically translatable tools for personalized diagnostics and targeted interventions in retinal disease.
Research Focus Areas:
Au A, Bajar BT, Wong BM, Daskivich LP, Hosseini H, Prasad PS
J Diabetes Complications (2024)
View PublicationAu A, Ip M, Blodi BA, Scott IU, Oden NL, Van Veldhuisen PC, Sarraf D
Am J Ophthalmol (2023)
View PublicationAu A, Santina A, Abraham N, Levin MF, Corradetti G, Sadda S, Sarraf D
Invest Ophthalmol Vis Sci (2022)
View PublicationHilely A, Au A, Freund KB, Loewenstein A, Souied EH, Zur D, Sacconi R, Borrelli E, Peiretti E, Iovino C, Sugiura Y, Ellabban AA, Monés J, Waheed NK, Ozdek S, Yalinbas D, Thiele S, de Moura Mendonça LS, Lee MY, Lee WK, Turcotte P, Capuano V, Filali Ansary M, Chakravarthy U, Lommatzsch A, Gunnemann F, Pauleikhoff D, Ip MS, Querques G, Holz FG, Spaide RF, Sadda S, Sarraf D
Br J Ophthalmol (2021)
View PublicationAu A, Hilely A, Scharf J, Gunnemann F, Wang D, Chehaibou I, Iovino C, Grondin C, Farecki ML, Falavarjani KG, Phasukkijwatana N, Battista M, Borrelli E, Sacconi R, Powell B, Hom G, Greenlee TE, Conti TF, Ledesma-Gil G, Teke MY, Choudhry N, Fung AT, Krivosic V, Baek J, Lee MY, Sugiura Y, Querques G, Peiretti E, Rosen R, Lee WK, Yannuzzi LA, Zur D, Loewenstein A, Pauleikhoff D, Singh R, Modi Y, Hubschman JP, Ip M, Sadda S, Freund KB, Sarraf D
Invest Ophthalmol Vis Sci (2020)
View Publication